Article
Polymorphisms in the ERCC5 gene and risk of esophageal squamous cell carcinoma (ESCC) in Eastern Chinese populations.
PloS one - 1 Jan 2012
Zhu Mei-Ling, Shi Ting-Yan, Hu Hai-Chuan, He Jing, Wang Mengyun, Jin Li, Yang Ya-Jun, Wang Jiu-Cun, Sun Meng-Hong, Chen Huan, Zhao Kuai-Le, Zhang Zhen, Chen Hai-Quan, Xiang Jia-Qing, Wei Qing-Yi
Abstract excerpt
BACKGROUND: Excision repair cross complementing group 5 (ERCC5 or XPG) plays an important role in regulating DNA excision repair; its functional single nucleotide polymorphisms (SNPs) may alter DNA repair capacity and thus contribute to cancer risk. METHODOLOGY/PRINCIPAL FINDINGS: In a hospital-based case-control study of 1115 esophageal squamous cell carcinoma (ESCC) cases and 1117 cancer-free controls, we...
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