Article
Functional polymorphisms of matrix metallopeptidase-9 and risk of coronary artery disease in a Chinese population.
Molecular biology reports - 1 Jan 2010
Zhi Hong, Wang Hua, Ren Liqun, Shi Zhiyang, Peng Haiyan, Cui Lunbiao, Ma Genshan, Ye Xingzhou, Feng Yi, Shen Chengxing, Zhai Xiangjun, Zhang Chenyu, Zen Ke, Liu Naifeng
Abstract excerpt
Matrix metallopeptidase-9 (MMP-9) plays a pivotal role in vascular remodeling and development of atherosclerotic lesion. The potentially functional MMP-9 polymorphisms may contribute to the susceptibility of coronary artery disease (CAD). A case-control study composed of 762 CAD cases and 555 CAD-free controls was conducted in a Chinese population to investigate the association between the MMP-9 -1562 C>T, R279Q,...
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