Article
Matrix Metalloproteinase-9 (MMP-9) Gene Polymorphism in Stroke Patients.
Neuromolecular medicine - 1 Dec 2015
Buraczynska Kinga, Kurzepa Jacek, Ksiazek Andrzej, Buraczynska Monika, Rejdak Konrad
Abstract excerpt
Matrix metalloproteinases (MMPs), endopeptidases degrading extracellular matrix, play an important role in the pathogenesis of atherosclerosis and vascular disease. The aim of this study was to evaluate the association between the C(-1562)T functional polymorphism in the MMP-9 gene and risk of stroke. We examined 322 patients with stroke and 410 controls. In the patient group, 52 % had type 2 diabetes. All...
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