Article
Matrix metalloproteinase-9 functional promoter polymorphism 1562C>T increased risk of early-onset coronary artery disease.
Molecular biology reports - 1 Jan 2012
Saedi Massoud, Vaisi-Raygani Asad, Khaghani Shahnaz, Shariftabrizi Ahmad, Rezaie M, Pasalar Parvin, Rahimi Zohreh, Pourmotabbed Tayebeh
Abstract excerpt
The Matrix metalloproteinase-9 functional promoter polymorphism 1562C>T may be considered an important genetic determinant of early-onset coronary artery disease (ECAD). In this study, association between MMP-9 1562C>T allele with plasma MMP-9 activity, homocysteine and lipid-lipoproteins level and ECAD in Iranian subjects was investigated. This case-control study consisted of 53 ECAD patients (age < 55 years)...
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