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Article

Single nucleotide polymorphisms in the D-loop region of mitochondrial DNA and age-at-onset of patients with chronic kidney disease.

Chinese medical journal - 1 Jan 2014

Bai Yaling, Guo Zhanjun, Xu Jinsheng, Zhang Junxia, Cui Liwen, Zhang Huiran, Zhang Shenglei, Ai Xiaolu

Abstract excerpt

BACKGROUND: The mitochondrial displacement loop (D-loop) accumulates mutations and single nucleotide polymorphisms (SNPs) at a higher frequency than other regions of mitochondrial DNA (mtDNA). We previously identified disease risk-associated SNPs in the D-loop of chronic kidney disease (CKD) patients; in this study, we investigated the association of age-at-onset and D-loop SNPs in CKD patients. METHODS: The...

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PMID: 25189950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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