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Article

CX3CR1-T280M polymorphism and end-stage renal disease development in chronic kidney disease.

Scientific reports - 3 Apr 2026

Gatti Matteo, Baragetti Ivano, Baragetti Andrea, Buzzi Laura, Lupi Andrea, Fassio Angelo, Olmastroni Elena, Catapano Alberico L, Fabbrini Paolo

Abstract excerpt

Chronic kidney disease (CKD) is a major global health concern driven by hypertension and diabetes, with genetic factors playing a key role in its pathogenesis. CX3CR1, the sole known receptor for the chemokine fractalkine, and its polymorphisms T280M and V249I have been implicated in the progression of several chronic diseases. This prospective observational study investigates the role of the CX3CR1 T280M...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 41932952
DOI: 10.1038/s41598-026-40013-8
PMCID: PMC13194959

Genes

CX3CR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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