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Association of mitochondrial DNA copy number with chronic kidney disease in older adults

24 Aug 2023

Abstract excerpt

BACKGROUND: Mitochondrial dysfunction in kidney cells has been implicated in the pathogenesis of chronic kidney disease (CKD). Estimation of mitochondrial DNA copy number (mtDNA-CN) is considered a convenient method for representing mitochondrial function in large samples. However, no study has investigated the association between mtDNA-CN and CKD in older adults with the highest prevalence. The objective is to...

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PMID: 37620817
DOI: 10.1186/s12877-023-04203-7

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