Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional Activation of Human CDCA8 Gene Regulated by Transcription Factor NF-Y in Embryonic Stem Cells and Cancer Cells

14 Jul 2015

Abstract excerpt

The cell division cycle associated 8 (CDCA8) gene plays an important role in mitosis. Overexpression of CDCA8 was reported in some human cancers and is required for cancer growth and progression. We found CDCA8 expression was also high in human ES cells (hESCs) but dropped significantly upon hESC differentiation. However, the regulation of CDCA8 expression has not yet been studied. Here, we characterized the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microtubule and mitosis dynamics
Share to Pancreatic function and diabetes
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26170459
DOI: 10.1074/jbc.m115.642710

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional Activation of Human CDCA8 Gene Regulated by Transcription Factor NF-Y in Embryonic Stem Cells and Cancer CellsPMID 26170459Read ↗

CDCA4 Is an E2F Transcription Factor Family-induced Nuclear Factor That Regulates E2F-dependent Transcriptional Activation and Cell ProliferationSemantic proximity Read ↗

CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell CarcinomaSemantic proximity Read ↗

KLF7 promotes neuroblastoma differentiation through regulation neuroblast differentiation-associated protein AHNAKs and is a marker of clinical outcomeSemantic proximity Read ↗

SAPCD2 promotes neuroblastoma progression by altering the subcellular distribution of E2F7Semantic proximity Read ↗

CENPA facilitates hepatocellular carcinoma proliferation by cooperating with YY1 to drive transcription of CCND1 and NRP2.Semantic proximity Read ↗

Systematic Analysis of the Clinical Relevance of Cell Division Cycle Associated Family in Endometrial CarcinomaSemantic proximity Read ↗

PCLAF promotes neuroblastoma G1/S cell cycle progression via the E2F1/PTTG1 axisSemantic proximity Read ↗

CENPU Promotes Growth and Metastasis in Nasopharyngeal Carcinoma by Inhibiting DUSP6Semantic proximity Read ↗

The diagnostic and prognostic value of cell division cycle associated gene family in Hepatocellular CarcinomaSemantic proximity Read ↗

Serum-dependent recruitment of the chromatin remodeler CHD8 to promoters is mediated by the ERK-ELK pathwaySemantic proximity Read ↗

Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genesSemantic proximity Read ↗

The C-terminal 4CXXC-type zinc finger domain of CDCA7 recognizes hemimethylated DNA and modulates activities of chromatin remodeling enzyme HELLS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.