Article
Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung.
Carcinogenesis - 1 Dec 2014
Nguyen Justin Dang Uy, Lamontagne Maxime, Couture Christian, Conti Massimo, Paré Peter D, Sin Don D, Hogg James C, Nickle David, Postma Dirkje S, Timens Wim, Laviolette Michel, Bossé Yohan
Abstract excerpt
Recent studies identified three genetic loci reproducibly associated with lung cancer in populations of European ancestry, namely 15q25, 5p15 and 6p21. The goals of this study are first to confirm whether these loci are associated with lung cancer in a French Canadian population and second to identify disease-associated single nucleotide polymorphisms (SNPs) influencing messenger RNA (mRNA) expression levels of...
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