Article
Ipsilateral Breast Carcinoma Recurrence: True Recurrence or New Primary? A Clinicopathologic and Molecular Study.
The American journal of surgical pathology - 1 Mar 2025
Fernández-Abad María, Caniego-Casas Tamara, Carretero-Barrio Irene, Calderay-Domínguez Milagros, Saavedra Cristina, Hardisson David, Palacios José, Pérez-Mies Belén
Abstract excerpt
Determining whether an ipsilateral breast carcinoma recurrence is a true recurrence or a new primary remains challenging based solely on clinicopathologic features. Algorithms based on these features have estimated that up to 68% of recurrences might be new primaries. However, few studies have analyzed the clonal relationship between primary and secondary carcinomas to establish the true nature of recurrences....
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