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Article

Influence of BDNF Val66Met on the relationship between physical activity and brain volume.

Neurology - 7 Oct 2014

Brown Belinda M, Bourgeat Pierrick, Peiffer Jeremiah J, Burnham Samantha, Laws Simon M, Rainey-Smith Stephanie R, Bartrés-Faz David, Villemagne Victor L, Taddei Kevin, Rembach Alan, Bush Ashley, Ellis Kathryn A, Macaulay S Lance, Rowe Christopher C, Ames David, Masters Colin L, Maruff Paul, Martins Ralph N

Abstract excerpt

OBJECTIVE: To investigate the association between habitual physical activity levels and brain temporal lobe volumes, and the interaction with the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism. METHODS: This study is a cross-sectional analysis of 114 cognitively healthy men and women aged 60 years and older. Brain volumes quantified by MRI were correlated with self-reported physical activity...

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Source

Identifiers

PMID: 25186863
DOI: 10.1212/WNL.0000000000000867

Genes

BDNF
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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