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Article

Longitudinal Effects of Physical Activity Change on Hippocampal Volumes over up to 12 Years in Middle and Older Age Community-Dwelling Individuals.

Cerebral cortex (New York, N.Y. : 1991) - 16 Jun 2022

Fraser Mark A, Walsh Erin I, Shaw Marnie E, Anstey Kaarin J, Cherbuin Nicolas

Abstract excerpt

The objectives of this study were to investigate the long-term associations between changes in physical activity levels and hippocampal volumes over time, while considering the influence of age, sex, and APOE-ε4 genotype. We investigated the effects of change in physical activity on hippocampal volumes in 411 middle age (mean age = 47.2 years) and 375 older age (mean age = 63.1 years) adults followed up to...

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PMID: 34671805
DOI: 10.1093/cercor/bhab375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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