Folding dynamics and pathways of the trp-cage miniproteins.

Abstract excerpt

Using alternate measures of fold stability for a wide variety of Trp-cage mutants has raised the possibility that prior dynamics T-jump measures may not be reporting on complete cage formation for some species. NMR relaxation studies using probes that only achieve large chemical shift difference from unfolded values on complete cage formation indicate slower folding in some but not all cases. Fourteen species...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Magnetic Resonance Spectroscopy
• Share to Mutation
• Share to Protein Conformation