Article
Genome-wide distribution of Auts2 binding localizes with active neurodevelopmental genes.
Translational psychiatry - 2 Sept 2014
Oksenberg N, Haliburton G D E, Eckalbar W L, Oren I, Nishizaki S, Murphy K, Pollard K S, Birnbaum R Y, Ahituv N
Abstract excerpt
The autism susceptibility candidate 2 gene (AUTS2) has been associated with multiple neurological diseases including autism spectrum disorders (ASDs). Previous studies showed that AUTS2 has an important neurodevelopmental function and is a suspected master regulator of genes implicated in ASD-related pathways. However, the regulatory role and targets of Auts2 are not well known. Here, by using ChIP-seq (chromatin...
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