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Article

Long genes linked to autism spectrum disorders harbor broad enhancer-like chromatin domains.

Genome research - 1 Jul 2018

Zhao Ying-Tao, Kwon Deborah Y, Johnson Brian S, Fasolino Maria, Lamonica Janine M, Kim Yoon Jung, Zhao Boxuan Simen, He Chuan, Vahedi Golnaz, Kim Tae Hoon, Zhou Zhaolan

Abstract excerpt

Genetic variants associated with autism spectrum disorders (ASDs) are enriched in genes encoding synaptic proteins and chromatin regulators. Although the role of synaptic proteins in ASDs is widely studied, the mechanism by which chromatin regulators contribute to ASD risk remains poorly understood. Upon profiling and analyzing the transcriptional and epigenomic features of genes expressed in the cortex, we...

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Identifiers

PMID: 29848492
DOI: 10.1101/gr.233775.117
PMCID: PMC6028126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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