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Article

Variation in the dopamine D2 receptor gene plays a key role in human pain and its modulation by transcranial magnetic stimulation.

Pain - 1 Oct 2014

Jääskeläinen Satu K, Lindholm Pauliina, Valmunen Tanja, Pesonen Ullamari, Taiminen Tero, Virtanen Arja, Lamusuo Salla, Forssell Heli, Hagelberg Nora, Hietala Jarmo, Pertovaara Antti

Abstract excerpt

We tested whether variation of the dopamine D2 receptor (DRD2) gene contributes to individual differences in thermal pain sensitivity and analgesic efficacy of repetitive transcranial magnetic stimulation (rTMS) in healthy subjects (n=29) or susceptibility to neuropathic pain in patients with neurophysiologically confirmed diagnosis (n=16). Thermal sensitivity of healthy subjects was assessed before and after...

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Source

Identifiers

PMID: 25180011
DOI: 10.1016/j.pain.2014.08.029

Genes

DRD2
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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