Article
Association between butyrylcholinesterase activity and phenotypes, paraoxonase192 rs662 gene polymorphism and their enzymatic activity with severity of rheumatoid arthritis: correlation with systemic inflammatory markers and oxidative stress, preliminary report.
Clinical biochemistry - 1 Jan 2015
Shahmohamadnejad Shiva, Vaisi-Raygani Asad, Shakiba Yadola, Kiani Amir, Rahimi Zohreh, Bahrehmand Fariborz, Shakiba Ebrahimi, Pourmotabbed Tayehbeh
Abstract excerpt
OBJECTIVES: Evidences indicate that oxidative stress and inflammation are important processes in the development of destructive synovial tissue in rheumatoid arthritis (RA). The two major bioscavenger enzymes that are associated with inflammation and oxidative stress are human-butyrylcholinesterase (BuChE) and paraoxonase-1 (PON-1). Thus, the objective of this study was to determine the relation of BuChE...
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