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Article

Relationships between paraoxon and 2-coumaranone hydrolytic activities in sera genotyped for PON1 Q192R polymorphism.

Clinical biochemistry - 1 Oct 2009

Giacominelli-Stuffler Roberto, Angelucci Clotilde Beatrice, Liberatoscioli Laura, Cortese Claudio, Dainese Enrico, Maccarrone Mauro

Abstract excerpt

OBJECTIVES: To set-up a method for a direct evaluation in human serum of paraoxonase enzymatic activities, establishing a possible correlation with Q192R genotype polymorphism. DESIGN AND METHODS: 101 different human serum samples were genotyped for paraoxonase Q192R polymorphism by PCR restriction analysis, and evaluated spectrophotometrically with regard to paraoxon and 2-coumaranone hydrolytic activities. Both...

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Source

Identifiers

PMID: 19615988
DOI: 10.1016/j.clinbiochem.2009.07.006

Genes

PON1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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