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Article

Carotid plaques in adult rheumatoid arthritis patients; association with paroxonase 1 enzymatic activity and Q192R paroxonase 1 gene polymorphism.

Molecular biology reports - 1 Jun 2020

Atwa Essam Tawfik, Hussin Atef Goda, Mohamed Mona Rabie, Pasha Heba Fouad, Hammad Marwa

Abstract excerpt

Paroxonase 1 (PON 1) enzymatic activity and Q192R PON polymorphism has been implicated with greater cardiovascular risk in general population. Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized with increased inflammatory markers leading to increased cardiovascular morbidity. The aim of the work was to study association between PON1 enzymatic activity & gene polymorphism with carotid plaques...

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PMID: 32472296
DOI: 10.1007/s11033-020-05558-5

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