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Article

Low DEFB4 copy number and high systemic hBD-2 and IL-22 levels are associated with dermatophytosis.

The Journal of investigative dermatology - 1 Mar 2015

Jaradat Sameh W, Cubillos Susana, Krieg Nadine, Lehmann Katja, Issa Bassam, Piehler Susann, Wehner-Diab Sylvi, Hipler Uta-Christina, Norgauer Johannes

Abstract excerpt

Dermatophytes initiate dermatophytosis, but susceptibility to infection is dictated by host genetic factors, although the role of some of these-such as human beta-defensin 2 (hBD-2) genomic (DEFB4) copy number (CN) variation and its induction by IL-22-remains unclear. This was investigated in thi...

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Identifiers

PMID: 25178103
DOI: 10.1038/jid.2014.369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25178103-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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