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Article

Determination of beta-defensin genomic copy number in different populations: a comparison of three methods.

PloS one - 22 Feb 2011

Fode Peder, Jespersgaard Cathrine, Hardwick Robert J, Bogle Helen, Theisen Michael, Dodoo Daniel, Lenicek Martin, Vitek Libor, Vieira Ana, Freitas Joao, Andersen Paal Skytt, Hollox Edward J

Abstract excerpt

BACKGROUND: There have been conflicting reports in the literature on association of gene copy number with disease, including CCL3L1 and HIV susceptibility, and β-defensins and Crohn's disease. Quantification of precise gene copy numbers is important in order to define any association of gene copy number with disease. At present, real-time quantitative PCR (QPCR) is the most commonly used method to determine gene...

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PMID: 21364933
DOI: 10.1371/journal.pone.0016768
PMCID: PMC3043064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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