Article
Leishmania amazonensis: Increase in ecto-ATPase activity and parasite burden of vinblastine-resistant protozoa.
Experimental parasitology - 1 Nov 2014
Giarola Naira Lígia Lima, Silveira Thaís Souza, Inacio Job Domingos Filho, Vieira Lisvane Paes, Almeida-Amaral Elmo Eduardo, Meyer-Fernandes José Roberto
Abstract excerpt
Leishmania amazonensis is a protozoan parasite that induces mucocutaneous and diffuse cutaneous lesions upon infection. An important component in treatment failure is the emergence of drug-resistant parasites. It is necessary to clarify the mechanism of resistance that occurs in these parasites to develop effective drugs for leishmaniasis treatment. Promastigote forms of L. amazonensis were selected by gradually...
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