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Article

Role of efflux pumps and intracellular thiols in natural antimony resistant isolates of Leishmania donovani.

PloS one - 1 Jan 2013

Rai Smita, Bhaskar, Goel Sudhir K, Nath Dwivedi Upendra, Sundar Shyam, Goyal Neena

Abstract excerpt

BACKGROUND: In view of the recent upsurge in the phenomenon of therapeutic failure, drug resistance in Leishmania, developed under natural field conditions, has become a great concern yet little understood. Accordingly, the study of determinants of antimony resistance is urgently warranted. Efflux transporters have been reported in Leishmania but their role in clinical resistance is still unknown. The present...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to Biological Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Intracellular Space

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Share to Membrane Transport Proteins

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Source

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Identifiers

PMID: 24069359
DOI: 10.1371/journal.pone.0074862
PMCID: PMC3775726

Genes

AQP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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