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Article

The pluripotency factor Nanog is directly upregulated by the Androgen Receptor in prostate cancer cells

31 Aug 2014

Abstract excerpt

BACKGROUND: The Androgen Receptor (AR) is a nuclear hormone receptor that functions as a critical oncogene in all stages of prostate cancer progression, including progression to castration-resistance following androgen-deprivation therapy. Thus, identifying and targeting critical AR-regulated genes is one potential method to block castration-resistant cancer proliferation. Of particular importance are...

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Share to Estrogen and related hormone effects
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 25175748
DOI: 10.1002/pros.22870

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