Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autophagy regulates tissue overgrowth in a context-dependent manner.

Oncogene - 1 Jun 2015

Pérez E, Das G, Bergmann A, Baehrecke E H

Abstract excerpt

Autophagy is a catabolic process that has been implicated both as a tumor suppressor and in tumor progression. Here, we investigate this dichotomy in cancer biology by studying the influence of altered autophagy in Drosophila models of tissue overgrowth. We find that the impact of altered autopha...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Cellular Microenvironment
Share to Epithelium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eye Abnormalities

Share to Genes, Insect

Share to Organogenesis

Share to ras Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25174403
DOI: 10.1038/onc.2014.285
PMCID: PMC4345156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25174403-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autophagy regulates tissue overgrowth in a context-dependent manner.PMID 25174403Read ↗

α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation.Semantic proximity Read ↗

Autophagy and mammalian development.Semantic proximity Read ↗

Developmentally regulated autophagy is required for eye formation in DrosophilaSemantic proximity Read ↗

ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase.Semantic proximity Read ↗

FOXO-regulated transcription restricts overgrowth of Tsc mutant organs.Semantic proximity Read ↗

Role and regulation of starvation-induced autophagy in the Drosophila fat body.Semantic proximity Read ↗

FoxO restricts growth and differentiation of cells with elevated TORC1 activity under nutrient restriction.Semantic proximity Read ↗

Misshapen Disruption Cooperates with RasV12 to Drive Tumorigenesis.Semantic proximity Read ↗

<i> Ras <sup>G12V</sup> </i> Oncogene-Induced Epithelial Senescence and Its Relay Promotes Host Metabolic Syndrome in <i>Drosophila</i>Semantic proximity Read ↗

Regulation of cell growth by autophagySemantic proximity Read ↗

Myc-driven overgrowth requires unfolded protein response-mediated induction of autophagy and antioxidant responses in Drosophila melanogaster.Semantic proximity Read ↗

Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.