Article
Autophagy and mammalian development.
Biochemical Society transactions - 1 Dec 2013
Wu Xiaoting, Won Hyeran, Rubinsztein David C
Abstract excerpt
Autophagy is a highly conserved cytoplasmic degradation pathway that has an impact on many physiological and disease states, including immunity, tumorigenesis and neurodegeneration. Recent studies suggest that autophagy may also have important functions in embryogenesis and development. Many autophagy gene-knockout mice have embryonic lethality at different stages of development. Furthermore, interactions of...
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