Article
Analysis of single-nucleotide polymorphisms in the APOBEC3H gene of domestic cats (Felis catus) and their association with the susceptibility to feline immunodeficiency virus and feline leukemia virus infections.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2014
de Castro Fernanda Luz, Junqueira Dennis Maletich, de Medeiros Rúbia Marília, da Silva Tailene Rabello, Costenaro Jamile Girardi, Knak Marcus Braga, de Matos Almeida Sabrina Esteves, Campos Fabrício Souza, Roehe Paulo Michel, Franco Ana Cláudia
Abstract excerpt
Feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) are widely distributed retroviruses that infect domestic cats (Felis catus). Restriction factors are proteins that have the ability to hamper retroviruses' replication and are part of the conserved mechanisms of anti-viral immunity of mammals. The APOBEC3 protein family is the most studied class of restriction factors; they are cytidine...
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