Article
Functions, structure, and read-through alternative splicing of feline APOBEC3 genes.
Genome biology - 1 Jan 2008
Münk Carsten, Beck Thomas, Zielonka Jörg, Hotz-Wagenblatt Agnes, Chareza Sarah, Battenberg Marion, Thielebein Jens, Cichutek Klaus, Bravo Ignacio G, O'Brien Stephen J, Löchelt Martin, Yuhki Naoya
Abstract excerpt
BACKGROUND: Over the past years a variety of host restriction genes have been identified in human and mammals that modulate retrovirus infectivity, replication, assembly, and/or cross-species transmission. Among these host-encoded restriction factors, the APOBEC3 (A3; apolipoprotein B mRNA-editing catalytic polypeptide 3) proteins are potent inhibitors of retroviruses and retrotransposons. While primates encode...
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