Article
Polymorphisms and tissue expression of the feline leukocyte antigen class I loci FLAI-E, FLAI-H, and FLAI-K.
Immunogenetics - 1 Sept 2013
Holmes Jennifer C, Holmer Savannah G, Ross Peter, Buntzman Adam S, Frelinger Jeffrey A, Hess Paul R
Abstract excerpt
Cytotoxic CD8+ T-cell immunosurveillance for intracellular pathogens, such as viruses, is controlled by classical major histocompatibility complex (MHC) class Ia molecules, and ideally, these antiviral T-cell populations are defined by the specific peptide and restricting MHC allele. Surprisingly, despite the utility of the cat in modeling human viral immunity, little is known about the feline leukocyte antigen...
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