Chemical interference with iron transport systems to suppress bacterial growth of Streptococcus pneumoniae.

Abstract excerpt

Iron is an essential nutrient for the growth of most bacteria. To obtain iron, bacteria have developed specific iron-transport systems located on the membrane surface to uptake iron and iron complexes such as ferrichrome. Interference with the iron-acquisition systems should be therefore an efficient strategy to suppress bacterial growth and infection. Based on the chemical similarity of iron and ruthenium, we...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to ATP-Binding Cassette Transporters
• Share to Biological Transport