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Article

Interplay between manganese and iron in pneumococcal pathogenesis: role of the orphan response regulator RitR.

Infection and immunity - 1 Feb 2013

Ong Cheryl-Lynn Y, Potter Adam J, Trappetti Claudia, Walker Mark J, Jennings Michael P, Paton James C, McEwan Alastair G

Abstract excerpt

Streptococcus pneumoniae (the pneumococcus) is a major human pathogen that is carried asymptomatically in the nasopharynx by up to 70% of the human population. Translocation of the bacteria into internal sites can cause a range of diseases, such as pneumonia, otitis media, meningitis, and bacteremia. This transition from nasopharynx to growth at systemic sites means that the pneumococcus needs to adjust to a...

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Identifiers

PMID: 23184523
DOI: 10.1128/IAI.00805-12
PMCID: PMC3553810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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