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Article

PmtA functions as a ferrous iron and cobalt efflux pump in Streptococcus suis

1 Jan 2019

Abstract excerpt

Transition metals are nutrients essential for life. However, an excess of metals can be toxic to cells, and host-imposed metal toxicity is an important mechanism for controlling bacterial infection. Accordingly, bacteria have evolved metal efflux systems to maintain metal homeostasis. Here, we established that PmtA functions as a ferrous iron [Fe(II)] and cobalt [Co(II)] efflux pump in Streptococcus suis, an...

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Identifiers

PMID: 31469035
DOI: 10.1080/22221751.2019.1660233

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