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Streptococcus pyogenesCovRS Mediates Growth in Iron Starvation and in the Presence of the Human Cationic Antimicrobial Peptide LL-37

8 Nov 2008

Abstract excerpt

We found that the global regulatory two-component signal transduction system CovRS mediates the ability of group A streptococcus (GAS) to grow under two stresses encountered during infection: iron starvation and the presence of LL-37. We also showed that CovRS regulates transcription of the multimetal transporter operon that is important for GAS growth in a low concentration of iron.

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Share to Antimicrobial Resistance in Staphylococcus
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Identifiers

PMID: 18996992
DOI: 10.1128/jb.01256-08

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