Article
A cis-regulatory mutation of PDSS2 causes silky-feather in chickens.
PLoS genetics - 1 Aug 2014
Feng Chungang, Gao Yu, Dorshorst Ben, Song Chi, Gu Xiaorong, Li Qingyuan, Li Jinxiu, Liu Tongxin, Rubin Carl-Johan, Zhao Yiqiang, Wang Yanqiang, Fei Jing, Li Huifang, Chen Kuanwei, Qu Hao, Shu Dingming, Ashwell Chris, Da Yang, Andersson Leif, Hu Xiaoxiang, Li Ning
Abstract excerpt
Silky-feather has been selected and fixed in some breeds due to its unique appearance. This phenotype is caused by a single recessive gene (hookless, h). Here we map the silky-feather locus to chromosome 3 by linkage analysis and subsequently fine-map it to an 18.9 kb interval using the identical by descent (IBD) method. Further analysis reveals that a C to G transversion located upstream of the prenyl...
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