Article
A cis-regulatory mutation in the EDN3 promoter drives coordinated formation of comb and skin color in Anyi gray chickens.
Poultry science - 1 Jun 2026
Huang Jianxi, Cheng Di, Xi Suwang, Wang Zun, Tu Yun, Huang Sixiang, Wu Dongxiao, Zhang Zengwei, Jiang Hongxia, Hu Xiaolong, Chen Biao, Liu Sanfeng, Mao Huirong
Abstract excerpt
Comb and skin pigmentation are key external traits in domestic chickens, closely correlated and serving as important visual cues for consumers. The Anyi Gray chicken, an indigenous breed from Jiangxi Province, China, exhibits two stable phenotypes: red comb with white skin (RAY), and purple-gray comb with purple-gray skin (PAY). Although skin color is completely linked to comb color, the genetic basis of this...
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