Article
Genome-wide SNP scan of pooled DNA reveals nonsense mutation in FGF20 in the scaleless line of featherless chickens.
BMC genomics - 19 Jun 2012
Wells Kirsty L, Hadad Yair, Ben-Avraham Danny, Hillel Jossi, Cahaner Avigdor, Headon Denis J
Abstract excerpt
BACKGROUND: Scaleless (sc/sc) chickens carry a single recessive mutation that causes a lack of almost all body feathers, as well as foot scales and spurs, due to a failure of skin patterning during embryogenesis. This spontaneous mutant line, first described in the 1950s, has been used extensively to explore the tissue interactions involved in ectodermal appendage formation in embryonic skin. Moreover, the trait...
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