Genome-Wide Identification of the Mutation Underlying Fleece Variation and Discriminating Ancestral Hairy Species from Modern Woolly Sheep.

doi:10.1093/molbev/msx114

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Genome-Wide Identification of the Mutation Underlying Fleece Variation and Discriminating Ancestral Hairy Species from Modern Woolly Sheep.

Molecular biology and evolution - 1 Jul 2017

Demars Julie, Cano Margarita, Drouilhet Laurence, Plisson-Petit Florence, Bardou Philippe, Fabre Stéphane, Servin Bertrand, Sarry Julien, Woloszyn Florent, Mulsant Philippe, Foulquier Didier, Carrière Fabien, Aletru Mathias, Rodde Nathalie, Cauet Stéphane, Bouchez Olivier, Pirson Maarten, Tosser-Klopp Gwenola, Allain Daniel

Abstract excerpt

The composition and structure of fleece variation observed in mammals is a consequence of a strong selective pressure for fiber production after domestication. In sheep, fleece variation discriminates ancestral species carrying a long and hairy fleece from modern domestic sheep (Ovis aries) owning a short and woolly fleece. Here, we report that the "woolly" allele results from the insertion of an antisense EIF2S2...

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PMID: 28379502
DOI: 10.1093/molbev/msx114
PMCID: PMC5455980

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