Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequencing of Charcot-Marie-Tooth disease genes in a toxic polyneuropathy.

Annals of neurology - 1 Nov 2014

Beutler Andreas S, Kulkarni Amit A, Kanwar Rahul, Klein Christopher J, Therneau Terry M, Qin Rui, Banck Michaela S, Boora Ganesh K, Ruddy Kathryn J, Wu Yanhong, Smalley Regenia L, Cunningham Julie M, Le-Lindqwister Nguyet Anh, Beyerlein Peter, Schroth Gary P, Windebank Anthony J, Züchner Stephan, Loprinzi Charles L

Abstract excerpt

OBJECTIVE: Mutations in Charcot-Marie-Tooth disease (CMT) genes are the cause of rare familial forms of polyneuropathy. Whether allelic variability in CMT genes is also associated with common forms of polyneuropathy-considered "acquired" in medical parlance-is unknown. Chemotherapy-induced peripheral neuropathy (CIPN) occurs commonly in cancer patients and is individually unpredictable. We used CIPN as a clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neoplasms
Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antineoplastic Agents

Share to Antineoplastic Agents, Phytogenic

Share to Charcot-Marie-Tooth Disease

Share to Paclitaxel

Share to Polyneuropathies

Share to Rho Guanine Nucleotide Exchange Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25164601
DOI: 10.1002/ana.24265
PMCID: PMC4388308

Genes

ARHGEF10
PRX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequencing of Charcot-Marie-Tooth disease genes in a toxic polyneuropathy.PMID 25164601Read ↗

Association of the Charcot-Marie-Tooth disease gene ARHGEF10 with paclitaxel induced peripheral neuropathy in NCCTG N08CA (Alliance).Semantic proximity Read ↗

Pharmacogenomics of chemotherapy induced peripheral neuropathy using an electronic health record-derived definition: a genome-wide association study.Semantic proximity Read ↗

Recent advances in the genetic neuropathies.Semantic proximity Read ↗

Genetic variation in Charcot-Marie-Tooth genes contributes to sensitivity to paclitaxel-induced peripheral neuropathy.Semantic proximity Read ↗

Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy.Semantic proximity Read ↗

Charcot-Marie-Tooth disease and related hereditary polyneuropathies: molecular diagnostics determine aspects of medical management.Semantic proximity Read ↗

Testing of candidate single nucleotide variants associated with paclitaxel neuropathy in the trial NCCTG N08C1 (Alliance).Semantic proximity Read ↗

Emerging Therapies for Charcot-Marie-Tooth Inherited Neuropathies.Semantic proximity Read ↗

Mechanistic insights into the pathogenesis of microtubule-targeting agent-induced peripheral neuropathy from pharmacogenetic and functional studies.Semantic proximity Read ↗

Hereditary Polyneuropathies in the Era of Precision Medicine: Genetic Complexity and Emerging Strategies.Semantic proximity Read ↗

Polygenic risk of paclitaxel-induced peripheral neuropathy: a genome-wide association studySemantic proximity Read ↗

Whole exome sequencing establishes diagnosis of Charcot-Marie-Tooth 4J, 1C, and X1 subtypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.