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Article

Two clinical phenotypes in polycythemia vera.

The New England journal of medicine - 28 Aug 2014

Spivak Jerry L, Considine Michael, Williams Donna M, Talbot Conover C, Rogers Ophelia, Moliterno Alison R, Jie Chunfa, Ochs Michael F

Abstract excerpt

BACKGROUND: Polycythemia vera is the ultimate phenotypic consequence of the V617F mutation in Janus kinase 2 (encoded by JAK2), but the extent to which this mutation influences the behavior of the involved CD34+ hematopoietic stem cells is unknown. METHODS: We analyzed gene expression in CD34+ peripheral-blood cells from 19 patients with polycythemia vera, using oligonucleotide microarray technology after...

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Share to Antigens, CD34
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oligonucleotide Array Sequence Analysis

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Source

Open in PubMed Open full text

Identifiers

PMID: 25162887
DOI: 10.1056/NEJMoa1403141
PMCID: PMC4211877

Genes

JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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