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Article

Clonal analyses reveal associations of JAK2V617F homozygosity with hematologic features, age and gender in polycythemia vera and essential thrombocythemia.

Haematologica - 1 May 2013

Godfrey Anna L, Chen Edwin, Pagano Francesca, Silber Yvonne, Campbell Peter J, Green Anthony R

Abstract excerpt

Subclones homozygous for JAK2V617F are more common and larger in patients with polycythemia vera compared to essential thrombocythemia, but their role in determining phenotype remains unclear. We genotyped 4564 erythroid colonies from 59 patients with polycythemia vera or essential thrombocythemia to investigate whether the proportion of JAK2V617F -homozygous precursors, compared to heterozygous precursors, is...

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Identifiers

PMID: 23633544
DOI: 10.3324/haematol.2012.079129
PMCID: PMC3640115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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