Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF-E2.

British journal of haematology - 1 Apr 2005

Goerttler Philipp S, Kreutz Clemens, Donauer Johannes, Faller Daniel, Maiwald Thomas, März Edith, Rumberger Brigitta, Sparna Titus, Schmitt-Gräff Annette, Wilpert Jochen, Timmer Jens, Walz Gerd, Pahl Heike L

Abstract excerpt

Summary The molecular aetiology of polycythaemia vera (PV) remains unknown and the differential diagnosis between PV and secondary erythrocytosis (SE) can be challenging. Gene expression profiling can identify candidates involved in the pathophysiology of PV and generate a molecular signature to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Diagnosis, Differential

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Erythroid-Specific DNA-Binding Factors

Share to Hematopoietic Stem Cells

Share to Polycythemia

Share to Polycythemia Vera

Share to Sp1 Transcription Factor

Share to Zinc Fingers

Source

Identifiers

PMID: 15801966
DOI: 10.1111/j.1365-2141.2005.05416.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15801966-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF-E2.PMID 15801966Read ↗

Transcriptional profiling of polycythemia vera identifies gene expression patterns both dependent and independent from the action of JAK2V617F.Semantic proximity Read ↗

AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2Semantic proximity Read ↗

Genetic Background of Polycythemia Vera.Semantic proximity Read ↗

Two clinical phenotypes in polycythemia vera.Semantic proximity Read ↗

RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling.Semantic proximity Read ↗

Molecular profiling of peripheral blood cells from patients with polycythemia vera and related neoplasms: Identification of deregulated genes of significance for inflammation and immune surveillanceSemantic proximity Read ↗

Downregulated KLF2 in polycythemia vera and essential thrombocythemia induces prothrombotic gene expressionSemantic proximity Read ↗

Polycythemia vera erythroid precursors exhibit increased proliferation and apoptosis resistance associated with abnormal RAS and PI3K pathway activation.Semantic proximity Read ↗

Iron homeostasis governs erythroid phenotype in polycythemia vera.Semantic proximity Read ↗

[Differential diagnosis of myeloproliferative neoplasms. Quantitative NF-E2 immunohistochemistry for differentiating between essential thrombocythemia and primary myelofibrosis].Semantic proximity Read ↗

Polycythemia vera and other primary polycythemias.Semantic proximity Read ↗

Altered gene expression in myeloproliferative disorders correlates with activation of signaling by the V617F mutation of Jak2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.