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Article

Epigenetic modifications in Alzheimer's disease: cause or effect?

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Piaceri Irene, Raspanti Beatrice, Tedde Andrea, Bagnoli Silvia, Sorbi Sandro, Nacmias Benedetta

Abstract excerpt

Alzheimer's disease (AD) is a multifactorial disorder induced by a combination of genetic and environmental factors, and epigenetic modifications could be the key to understand the pathogenesis of AD. We performed a methylation study of the promoter regions of the three AD principal causative genes in 60 late-onset AD patients and 60 controls. The studied regions in the three causative genes were strongly...

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PMID: 25159670
DOI: 10.3233/JAD-141452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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