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Article

Clinical and metabolic parameters in non-small cell lung carcinoma and colorectal cancer patients with and without KRAS mutations.

International journal of environmental research and public health - 25 Aug 2014

Yilmaz Ahmet, Mohamed Nehad, Patterson Kara A, Tang Yan, Shilo Konstantin, Villalona-Calero Miguel A, Davis Michael E, Zhou Xiao-Ping, Frankel Wendy, Otterson Gregory A, Zhao Weiqiang

Abstract excerpt

Lung cancer (LC) and colorectal cancer (CRC) are the first and second deadliest types of cancer worldwide. EGFR-based therapy has been used in the treatment of these cancers with variable success. Presence of mutations in the KRAS driver oncogene, possibly induced by environmental factors such as carcinogens in diet and cigarette smoke, may confer worse prognosis and resistance to treatment for reasons not fully...

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Identifiers

PMID: 25158139
DOI: 10.3390/ijerph110908645
PMCID: PMC4198984

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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