Article
Lipoprotein lipase variants interact with polyunsaturated fatty acids for obesity traits in women: replication in two populations.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Dec 2014
Ma Y, Tucker K L, Smith C E, Lee Y C, Huang T, Richardson K, Parnell L D, Lai C Q, Young K L, Justice A E, Shao Y, North K E, Ordovás J M
Abstract excerpt
BACKGROUND AND AIMS: Lipoprotein lipase (LPL) is a candidate gene for obesity based on its role in triglyceride hydrolysis and the partitioning of fatty acids towards storage or oxidation. Whether dietary fatty acids modify LPL associated obesity risk is unknown. METHODS AND RESULTS: We examined five single nucleotide polymorphisms (SNPs) (rs320, rs2083637, rs17411031, rs13702, rs2197089) for potential...