Dietary fat modulation of hepatic lipase variant -514 C/T for lipids: a crossover randomized dietary intervention trial in Caribbean Hispanics.

doi:10.1152/physiolgenomics.00036.2017

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Article

Dietary fat modulation of hepatic lipase variant -514 C/T for lipids: a crossover randomized dietary intervention trial in Caribbean Hispanics.

Physiological genomics - 1 Oct 2017

Smith C E, Van Rompay M I, Mattei J, Garcia J F, Garcia-Bailo B, Lichtenstein A H, Tucker K L, Ordovás J M

Abstract excerpt

The hepatic lipase (LIPC) locus is a well-established determinant of high-density lipoprotein cholesterol (HDL-C) concentrations, an association that is modified by dietary fat in observational studies. Dietary interventions are lacking. We investigated dietary modulation of LIPC rs1800588 (-514 C/T) for lipids and glucose using a randomized crossover design comparing a high-fat Western diet and a low-fat...

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Identifiers

PMID: 28939642
DOI: 10.1152/physiolgenomics.00036.2017
PMCID: PMC5668648

Genes

LIPC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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