Article
The influence of renal function on the association of rs854560 polymorphism of paraoxonase 1 gene with long-term prognosis in patients after myocardial infarction.
Heart and vessels - 1 Jan 2016
Szpakowicz Anna, Pepinski Witold, Waszkiewicz Ewa, Maciorkowska Dominika, Skawronska Małgorzata, Niemcunowicz-Janica Anna, Dobrzycki Sławomir, Musial Włodzimierz J, Kaminski Karol A
Abstract excerpt
Paraoxonase 1 (PON1) is an enzyme responsible for the antioxidant properties of high density lipoprotein (HDL). The activity of PON1 is decreased in patients with coronary artery disease, myocardial infarction or chronic kidney disease. rs662 and rs854560 are single nucleotide polymorphisms (SNPs) associated with PON1 activity and 10-year cardiovascular mortality of patients with stable coronary artery disease....
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