Article
PAI-1 4G/5G and ACE I/D gene polymorphisms and the occurrence of myocardial infarction in patients on intermittent dialysis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jun 2003
Aucella Filippo, Margaglione Maurizio, Vigilante Mimmo, Gatta Giuseppe, Grandone Elvira, Forcella Mauro, Ktena Maria, De Min Alva, Salatino Giovanna, Procaccini Deni Aldo, Stallone Carmine
Abstract excerpt
BACKGROUND: Myocardial infarction (MI) is a leading cause of death, particularly in high-risk settings such as uraemia, in which it is not yet known to what extent genetic factors contribute to the overall risk of MI. We have prospectively evaluated the effect of plasminogen activator inhibitor-1 (PAI-1) 4G/5G and angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphisms on the occurrence of MI...
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