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Article

Genetic polymorphisms of paraoxonase-1 are associated with chronic kidney disease in Japanese women.

Kidney international - 1 Jul 2009

Ichikawa Kazunobu, Konta Tsuneo, Emi Mitsuru, Toriyama Sayumi, Takasaki Satoshi, Ikeda Ami, Shibata Yoko, Takabatake Noriaki, Takeishi Yasuchika, Kato Takeo, Kawata Sumio, Kubota Isao

Abstract excerpt

Paraoxonase-1 (PON1) is an HDL cholesterol-associated antioxidant enzyme, and some of its polymorphisms are linked with systemic oxidative stress and cardiovascular events. In this study, we genotyped seven single nucleotide polymorphisms (SNPs) within the PON1 gene and determined their association with chronic kidney disease in 2,968 individuals from the general Japanese population. We found that a missense SNP...

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Identifiers

PMID: 19357718
DOI: 10.1038/ki.2009.97

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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