Article
PbSR is synthesized in macrogametocytes and involved in formation of the malaria crystalloids.
Molecular microbiology - 1 Jun 2008
Carter Victoria, Shimizu Shoichi, Arai Meiji, Dessens Johannes T
Abstract excerpt
Crystalloids are transient organelles that form in developing malaria ookinetes and disappear after ookinete-to-oocyst transition. Their origins and functions remain poorly understood. The Plasmodium berghei scavenger receptor-like protein PbSR is essential for mosquito-to-host transmission of the parasite: PbSR knockout parasites produce normal numbers of oocysts that fail to form sporozoites, pointing to a role...
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