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Plasmodium SAS4: basal body component of male cell which is dispensable for parasite transmission

12 May 2022

Abstract excerpt

The centriole/basal body (CBB) is an evolutionarily conserved organelle acting as a microtubule organising centre (MTOC) to nucleate cilia, flagella, and the centrosome. SAS4/CPAP is a conserved component associated with BB biogenesis in many model flagellated cells. Plasmodium, a divergent unicellular eukaryote and causative agent of malaria, displays an atypical, closed mitosis with an MTOC (or centriolar...

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PMID: 35550346
DOI: 10.26508/lsa.202101329

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